Vol 5 Issue 2 April 2017-June 2017

Abstract: Some selected medicinal plants used by Myanmar people were evaluated for potential antioxidant and antimicrobial properties. In this study, the antioxidant activity of 14 types of medicinal plants  collected from Kyaukse origin of Mandalay Division in the country Myanmar was estimated using1, 1-diphenyl-2-picryl-hydrazyl (DPPH), ferric reducing antioxidant power (FRAP) assay and total phenol content assay. The highest antioxidant activity was demonstrated by Vitis vinifer Linn. Phyllanthus urinaria and Zingiber officinale in all tested in vitro antioxidant assays. As far as antimicrobial activity is concerned, ethanolic extracts of Vitis vinifer Linn, Sida acuta, Phyllanthus urinaria, Z. officinale Calendula officinalis Caccinia Indica and Curcuma Longa were found to be most potent against clinically important bacteria Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Enterococcus faecalis. Brine shrimp lethality test was also conducted to examine the toxicity of selected plant extracts. The experimental results suggest that all the tested plant extracts are non-toxic and no potential health risk for human consumption.

Keywords: Medicinal plants, Myanmar, Antioxidant, Antimicrobial activity, Toxicity.

Title: Determination of Antioxidant and Antimicrobial Potential of Some Myanmar Medicinal Plants

Author: Yadanar Win Myint, Thinzar Toe, Su Win Aye

International Journal of Life Sciences Research     

ISSN 2348-313X (Print), ISSN 2348-3148 (online)

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Abstract: The objective of this study was to isolate and identify the oral microorganisms implicated in oral infections in the population and also to evaluate and classify the effectiveness of common dental medicaments. The study tested the potency of the medicaments against oral microorganisms.

Methods: Bacteriological investigation was done on (140) oral samples. The samples were cultured in aerobic and anaerobic conditions on non-selective and selective media. Standard procedures of bacterial culture and identification were applied. Nine medicaments were utilized to test for sensitivity levels against isolates from the oral cavity. 

Results: 12 microbes were identified. Some were pathogenic while others were opportunistic organisms. The highest sensitivity was demonstrated by Acinetobacter calcoaceticus and Proteus mirabilis. The lowest sensitivity was seen in Pseudomonas aeruginosa and Hafnia alvei. The most effective medicament against the isolates was Formocresol and the least effective medicament was Calcium hydroxide. Bacterial Survival Index test was performed to show the sum of colony formation units. The lowest survival rate was found in Formocresol dilutions while the highest survival rate was found in Calcium Hydroxide dilutions indicative of sensitivity and resistance respectively. Restriction enzyme analysis showed varying banding patterns among the DNA of the organisms. Unique bands were seen with varying sizes of 8,000 base pairs to 23,000 base pairs.

Conclusion: The oral microorganisms may have implications on the health of individuals harboring them. Therefore, the knowledge of medicaments and microorganism that inhabit the oral cavity is important in predicting and preventing not only dental diseases but also associated systemic complications.

Keywords: Oral infections, microbes, medicaments, biofilm.

Title: The Biochemical Response of Oral Microorganisms to Common Dental Medicaments in Jamaica

Author: Paul Gyles, Ph.D., Gad Onywere, M.Sc., Phillip Mighty Dental Surgeon (DDS), Patience Bazuaye-Alonge, Ph.D.

International Journal of Life Sciences Research     

ISSN 2348-313X (Print), ISSN 2348-3148 (online)

Research Publish Journals