Abstract: Medicinal plants have been used from centuries to treat infectious diseases as an alternative form of health care. Even though pharmacological industries have produced a number of new antibiotics in the last decades, resistance to these antibiotics by microorganisms have increased. The present study evaluated the antimicrobial effect of Psidiumguajava L. and Carica papaya L. as used in the traditional system of medicine. Their effects were determined using standard method (agar well diffusion). The results obtained showed that both plants had a broad spectrum effect on the test isolates with zones of inhibition ranging from 16.0 to 14.0 mm for P. guajava and C. papaya at 200 mg/ml respectively for S. aureus, 18.4 to 13.0 mm for E. coli, 15.0 to 13.5 mm for S. typhi, 16.5 to 14.0 mm for Pseudomonas spp and 13.0 to 11.8 mm for C. albican respectively. Psidiumguajava showed more effect compared to Carica papaya with MIC at 50 mg/ml and 100 mg/ml respectively. The paper therefore reports the broad spectrum antimicrobial activities of Psidiumguajava L. and Carica papaya L. leaf extracts on different clinical isolates.
Keywords: Psidiumguajava L., Carica papaya L., antimicrobial, minimum inhibiting concentration, ethanol extract, aqueous extract.
Title: Antimicrobial Effect of the Leaf Extract of Psidiumguajava L. and Carica Papaya L.
Author: Ekaiko Marshall U, Arinze Adibelem G, John Wisdom O, Ajah Obinna
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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