Cow’s milk -An unusual cause of Methemoglobinemia in an infant

Dr. Venkatesh.H.A

Abstract: Methaemoglobinemia is a haematological disorder in which the iron within the haemoglobin molecule is oxidised from the ferrous to ferric state impairing the transport of oxygen causing cyanosis in children. The normal methhemoglobin level in blood is approximately 1%. 1Methaemoglobinemiacan occur due to inherited problems ordue to acquired causes (ingestion of certain drugs and  chemicals, cow’s milk allergy).The inherited form is usually due to deficient activity of NADH cytochrome b5 reductase. 2,3Neither of these causes occurs frequently but the treating physician must be aware of them. The nitrate induced Methaemoglobimemia is encountered frequently in infants less than 6months. Diagnosis is made by spectroscopic analysis of blood revealing characteristic absorption spectrum methemoglobin and electrophoresis can be used to confirm the presence of abnormal haemoglobin. Methylene blue is used in the treatment. We report a case in which one month old infant presented with Methaemoglobimemia following cow’s milk ingestion.

Keywords: Cyanosis, cow’s milk, diarrhoea, methemoglobinemia, methyleneblue.

Title: Cow’s milk -An unusual cause of Methemoglobinemiain an infant

Author: Dr. Venkatesh.H.A

International Journal of Life Sciences Research

ISSN 2348-3148(online), ISSN 2348-313X (Print)

Research Publish Journals

Vol. 2, Issue 3, July 2014 - September 2014

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Cow’s milk -An unusual cause of Methemoglobinemia in an infant by Dr. Venkatesh.H.A