Abstract: Gestational diabetes mellitus (GDM) is a common metabolic complication in pregnancy affecting the maternal and foetal wellbeing.
Aim: - The aim of this original research article is to investigate the histological changes in placenta of GDM and control women.
Method: - This study was done in Rama Medical College & Hospital Kanpur. Placenta sample from 50 cases of GDM and 150 of control women collected and histological changes studied.
Result: - In this study, the histological changes revealed that Fibrin was in 78% of GDM. Calcification was seen in 42% of GDM. Infarction was found in 4% of GDM. Chorioamnionitis was in 18% of GDM, but in control the histological changes revealed Fibrin in 40%, Calcification was 25.3%, Infarction was 4% and Chorioamnionitis was in 32%.
Conclusion: - Gestational diabetes mellitus causes significant histological changes but chorioamnionitis remains insignificant.
Keywords: GDM, Gestational diabetes mellitus, Placenta, Fibrin, Calcification, Infarction, Chorioamnionitis.
Title: GESTATIONAL DIABETES MELLITUS LEAD TO HISTO PATHOLOGICAL CHANGES IN PLACENTA IN NORTH INDIA
Author: Dr. Rakesh Kumar Shukla, Dr. R. K Srivastava, Dr. Anil Kumar, Dr. Archana Mishra
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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