Green Synthesis of Silver Nanoparticles and Their Antibacterial Activities of the Crude Extracts of Brucea Antidysenterica Leaves

Abstract: The aim of this study was to synthesize silver nanoparticle from the crude extracts of Brucea antidysenterica leaves in order to find possible sources for future novel antibacterial activity in pharmaceutical formulations. Silver nanoparticles were prepared by chemical reduction method and it was confirmed with the help of UV-Vis absorption spectroscopy and compared its antibacterial activity with 80%methanol crude extract. The synthesis of nanoparticles was confirmed by change in colour from yellowish to dark brown. Further, it was confirmed by UV-Vis spectrometer which the biosynthesis of silver nanoparticles. The peak is clearly visible around 438 nm which indicate the reduction of silver ions occurred due to the water-soluble phytochemicals present in the leaf extract. The synthesized silver nanoparticles have strong antibacterial activity against E.coli and S.aureus than standard and 80%methanol extract. A very low concentration of silver nanoparticle (0.008mg/mL) gave antibacterial performance. Applications of Ag nanoparticle based on these finding may lead to valuable discoveries in various fields such as medical devices and antimicrobial systems. Leaf of Brucea antidysenterica can be used as source of silver nanoparticle to prevent diseases associated with antibacterial activity. Keywords: antibacterial activity, Brucea antidysenterica, nanoparticle, E.coli. Title: Green Synthesis of Silver Nanoparticles and Their Antibacterial Activities of the Crude Extracts of Brucea Antidysenterica Leaves Author: Abraham Dilnesa, Dr. M. Alemayehu, Dr.A.Atakilt International Journal of Mathematics and Physical Sciences Research ISSN 2348-5736 (Online) Research Publish Journals

Citation