Low Dose Clozapine with Lamotrigine Augmentation in Treatment Resistance Schizophrenia: A Case Report

Alkhamees Abdulmajeed

Abstract: The initial clozapine dose is 12.5 mg, increasing gradually to 300-400 mg/d, up to a licensed maximum of 900 mg/d. A plasma level of 350 μg/L should be aimed for to ensure an adequate trial, but response may occur at lower plasma level, depending on many factors including augmentation and Ethnicity, here we present the case of a 24-year-old Saudi male with refractory schizophrenia who responded to low dose of clozapine and lamotrigine augmentation.

Keywords: clozapine; lamotrigine; Treatment Resistance Schizophrenia.

Title: Low Dose Clozapine with Lamotrigine Augmentation in Treatment Resistance Schizophrenia: A Case Report

Author: Alkhamees Abdulmajeed

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol. 6, Issue 1, April 2018 – September 2018

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Low Dose Clozapine with Lamotrigine Augmentation in Treatment Resistance Schizophrenia: A Case Report by Alkhamees Abdulmajeed