Abstract: Sea buckthorn, or Hippophae rhamnoides L., is a highly prized medicinal and nutritious plant that is found throughout Europe and Asia, especially in the Himalayan regions. It is a member of the Elaeagnaceae family. The plant's berries, leaves, seeds, and oils have historically been utilized in Tibetan, Mongolian, Chinese, Russian, and Ayurvedic medical systems to treat a variety of illnesses. Sea buckthorn's remarkable phytochemical variety and wide range of biological functions have attracted a lot of scientific attention in recent decades. The botanical traits, geographic range, ethnomedical importance, phytochemical composition, nutritional value, pharmacological activities, clinical evidence, safety profile, and commercial applications of H. rhamnoides are all well covered in this review. Numerous bioactive components, such as flavonoids (isorhamnetin, quercetin, kaempferol, and rutin), phenolic acids, carotenoids, tocopherols, phytosterols, vitamins, essential fatty acids, amino acids, and other antioxidant chemicals, are found in sea buckthorn, according to published research. Through a variety of molecular mechanisms including free radical scavenging, modulation of inflammatory pathways, and enhancement of endogenous antioxidant defenses, these phytochemicals collectively contribute to its powerful antioxidant, anti-inflammatory, antidiabetic, cardioprotective, hepatoprotective, neuroprotective, anticancer, gastroprotective, wound-healing, and immunomodulatory effects. Additionally, sea buckthorn's exceptional nutritional profile which includes high concentrations of vitamin C, carotenoids, dietary fiber, and special omega fatty acids supports its expanding use as a component of functional foods and nutraceuticals.
Despite significant advancements in understanding its phytochemistry and therapeutic potential, the majority of the information now available comes from in vitro and animal studies, and there are still few standardized dosage forms and carefully planned human trials. The creation of standardized solid oral formulations, especially antioxidant tablet formulations using optimal sea buckthorn extracts, has received very little attention, despite the fact that sea buckthorn has showed strong antioxidant activity. Future studies aiming at converting its antioxidant activity into evidence-based pharmaceutical formulations with enhanced stability, patient compliance, and therapeutic application should take advantage of this significant research void.
Key Words: Hippophae rhamnoides; sea buckthorn; phytochemistry; nutritional value; antioxidant activity; pharmacological activities; nutraceuticals; pharmaceutical formulations; antioxidant tablets.
Title: Sea Buckthorn (Hippophae rhamnoides L.): Phytochemistry, Pharmacological Prospective and the Emerging Opportunity for Anti Oxidant Tablet Formulation
Author: Subhra Swaraj, Mr. Rahul Sharma, Dr. Subhranshu Panda
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Vol. 14, Issue 2, April 2026 - June 2026
Page No: 97-118
Research Publish Journals
Website: www.researchpublish.com
Published Date: 30-June-2026
