Abstract: In this article, the chemistry of Quinolinyl Chalcones has been laid bare and shows that Quinolinyl Chalcones is a derivative of Chalcones and one of the secondary metabolites of natural products. The structural elucidation by IR (Infrared), NMR (Nuclear Magnetic Resonance), MS (Mass Spectrometry) of Quinolinyl Chalcones are concisely studied and reveal the Canonical structures of various Quinolinyl compounds. This article went further to explain, the different methods (Grinding Conventional heating and Ultrasound-Assisted) of Quinolinyl Chalcones synthesis, with comparison made of Conventional heating and Ultrasound-Assisted methods. More so, the diverse applications of Quinolinyl Chalcones in the treatment of various diseases such as HIV, Inflammatory, Malaria, Bacteria and Cancer etc. are extensively dealt with, which is supported by the Structural-Activity Relationship (SAR) of the compound (ie the arrangement and distribution of functional groups).
Keywords: Quinolines, Chalcones, Quinolinyl Chalcones, Structural Elucidation, Synthesis, Structural-Activity Relationship, Pharmacological Applications.
Title: THE CHEMISTRY OF QUINOLINYL CHALCONES
Author: Anyiam Ngozi Donald
International Journal of Thesis Projects and Dissertations (IJTPD)
Research Publish Journals
